Ultraproct N Overdosage

Symptoms: The results of investigations of the acute toxic potential of the active substances in Ultraproct N show that there is no risk of acute toxic symptoms following accidental overdosage during a single rectal or perianal application of Ultraproct N to be expected. After accidental oral ingestion of the preparation (e.g. ingestion of several grams of cream), the main symptoms to be expected are likely to be systemic effects of lignocaine hydrochloride, which, depending on dose, may be manifested in the form of severe cardiovascular symptoms (depression of cardiac function or cardiac arrest in extreme cases) or symptoms related to the central nervous system (convulsions, dyspnoea or respiratory failure in extreme cases).
Management: The management of an overdose includes close monitoring of vital functions, supportive care including oxygen supply, and symptomatic treatment of central and cardiovascular symptoms (e g. including short acting barbiturates, beta-sympathomimetics, atropine). Dialysis is of negligible value.